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April 2020

ContentsAre Alcohol Withdrawal Seizures Dangerous?What Are Seizures?Clinical vignetteComparison to previous studiesAlcohol-Related Seizures Chronic use of alcohol leads to changes in brain chemistry especially in the GABAergic system. Various adaptations occur such as changes in gene expression and down regulation of GABAA receptors. During acute alcohol withdrawal, changes also occur such as upregulation of alpha4 containing GABAA receptors and downregulation of alpha1 and alpha3 containing GABAA receptors....

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